Michael Gropper, MD, PhD

PARC Executive Sponsor
Professor and Chair
Anesthesia and Perioperative Care
+1 415 476-9035

Dr. Gropper, Chair of the UCSF Department of Anesthesia and Perioperative Care, is the executive sponsor for the PARC initiative. The PARC has also formed an advisory board that brings together faculty leaders from across the university with expertise in pain management, drug development, addiction medicine, and behavioral science to discover new and innovative methods for reducing pain.

UCSF Research Profile

Publications: 

A Least Absolute Shrinkage and Selection Operator-Derived Predictive Model for Postoperative Respiratory Failure in a Heterogeneous Adult Elective Surgery Patient Population.

CHEST critical care

Stocking JC, Taylor SL, Fan S, Wingert T, Drake C, Aldrich JM, Ong MK, Amin AN, Marmor RA, Godat L, Cannesson M, Gropper MA, Utter GH, Sandrock CE, Bime C, Mosier J, Subbian V, Adams JY, Kenyon NJ, Albertson TE, Garcia JGN, Abraham I

Outcomes and risk factors for delayed-onset postoperative respiratory failure: a multi-center case-control study by the University of California Critical Care Research Collaborative (UC3RC).

BMC anesthesiology

Stocking JC, Drake C, Aldrich JM, Ong MK, Amin A, Marmor RA, Godat L, Cannesson M, Gropper MA, Romano PS, Sandrock C, Bime C, Abraham I, Utter GH

Quality of Life Improvement: A Novel Framework and Approach to Well-Being.

Anesthesiology clinics

Sinskey JL, Chang JM, Nicholau D, Gropper MA

Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.

The New England journal of medicine

Hughes CG, Mailloux PT, Devlin JW, Swan JT, Sanders RD, Anzueto A, Jackson JC, Hoskins AS, Pun BT, Orun OM, Raman R, Stollings JL, Kiehl AL, Duprey MS, Bui LN, O'Neal HR, Snyder A, Gropper MA, Guntupalli KK, Stashenko GJ, Patel MB, Brummel NE, Girard TD, Dittus RS, Bernard GR, Ely EW, Pandharipande PP

Risk Factors Associated With Early Postoperative Respiratory Failure: A Matched Case-Control Study.

The Journal of surgical research

Stocking JC, Drake C, Aldrich JM, Ong MK, Amin A, Marmor RA, Godat L, Cannesson M, Gropper MA, Romano PS, Utter GH

Consensus-based perioperative protocols during the COVID-19 pandemic.

Journal of neurosurgery. Spine

Mummaneni PV, Burke JF, Chan AK, Sosa JA, Lobo EP, Mummaneni VP, Antrum S, Berven SH, Conte MS, Doernberg SB, Goldberg AN, Hess CP, Hetts SW, Josephson SA, Kohi MP, Ma CB, Mahadevan VS, Molinaro AM, Murr AH, Narayana S, Roberts JP, Stoller ML, Theodosopoulos PV, Vail TP, Wienholz S, Gropper MA, Green A, Berger MS

Postoperative respiratory failure: An update on the validity of the Agency for Healthcare Research and Quality Patient Safety Indicator 11 in an era of clinical documentation improvement programs.

American journal of surgery

Stocking JC, Utter GH, Drake C, Aldrich JM, Ong MK, Amin A, Marmor RA, Godat L, Cannesson M, Gropper MA, Romano PS

Developing a Comprehensive Model of Intensive Care Unit Processes: Concept of Operations.

Journal of patient safety

Romig M, Tropello SP, Dwyer C, Wyskiel RM, Ravitz A, Benson J, Gropper MA, Pronovost PJ, Sapirstein A

Intensive care unit providers more quickly and accurately assess risk of multiple harms using an engineered safety display.

Health informatics journal

Romig M, Carolan H, Ravitz A, Schell-Chaple H, Yoon E, Dwyer C, Thornton K, Gropper M, Pronovost PJ, Sapirstein A

Interprofessional Care and Teamwork in the ICU.

Critical care medicine

Donovan AL, Aldrich JM, Gross AK, Barchas DM, Thornton KC, Schell-Chaple HM, Gropper MA, Lipshutz AKM

Dr Ted Eger Obituary.

Anesthesia and analgesia

Gropper MA, Shafer SL

Preventing Harm in the ICU-Building a Culture of Safety and Engaging Patients and Families.

Critical care medicine

Thornton KC, Schwarz JJ, Gross AK, Anderson WG, Liu KD, Romig MC, Schell-Chaple H, Pronovost PJ, Sapirstein A, Gropper MA, Lipshutz AKM

Differentiating pulmonary transfusion reactions using recipient and transfusion factors.

Transfusion

Roubinian NH, Looney MR, Keating S, Kor DJ, Lowell CA, Gajic O, Hubmayr R, Gropper M, Koenigsberg M, Wilson GA, A Matthay M, Toy P, Murphy EL

An Ethnographic Study of Health Information Technology Use in Three Intensive Care Units.

Health services research

Leslie M, Paradis E, Gropper MA, Kitto S, Reeves S, Pronovost P

A Typology of ICU Patients and Families from the Clinician Perspective: Toward Improving Communication.

Health communication

Leslie M, Paradis E, Gropper MA, Milic MM, Kitto S, Reeves S, Pronovost P

IV Immunoglobulin: A Useful Tool for the Severe Pneumonia Toolbox?

Critical care medicine

Crowley JC, Gropper MA

Interprofessional rhetoric and operational realities: an ethnographic study of rounds in four intensive care units.

Advances in health sciences education : theory and practice

Paradis E, Leslie M, Gropper MA

A Clinical Trial to Detect Subclinical Transfusion-induced Lung Injury during Surgery.

Anesthesiology

Feiner JR, Gropper MA, Toy P, Lieberman J, Twiford J, Weiskopf RB

An analysis of near misses identified by anesthesia providers in the intensive care unit.

BMC anesthesiology

Lipshutz AK, Caldwell JE, Robinowitz DL, Gropper MA

Preoperative medical testing in Medicare patients undergoing cataract surgery.

The New England journal of medicine

Chen CL, Lin GA, Bardach NS, Clay TH, Boscardin WJ, Gelb AW, Maze M, Gropper MA, Dudley RA

Cytokines and clinical predictors in distinguishing pulmonary transfusion reactions.

Transfusion

Roubinian NH, Looney MR, Kor DJ, Lowell CA, Gajic O, Hubmayr RD, Gropper MA, Koenigsberg M, Wilson GA, Matthay MA, Toy P, Murphy EL

Recipient clinical risk factors predominate in possible transfusion-related acute lung injury.

Transfusion

Toy P, Bacchetti P, Grimes B, Gajic O, Murphy EL, Winters JL, Gropper MA, Hubmayr RD, Matthay MA, Wilson G, Koenigsberg M, Lee DC, Hirschler NV, Lowell CA, Schuller RM, Gandhi MJ, Norris PJ, Mair DC, Sanchez Rosen R, Looney MR

Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*.

Critical care medicine

Looney MR, Roubinian N, Gajic O, Gropper MA, Hubmayr RD, Lowell CA, Bacchetti P, Wilson G, Koenigsberg M, Lee DC, Wu P, Grimes B, Norris PJ, Murphy EL, Gandhi MJ, Winters JL, Mair DC, Schuller RM, Hirschler NV, Rosen RS, Matthay MA, Toy P

Delivering interprofessional care in intensive care: a scoping review of ethnographic studies.

American journal of critical care : an official publication, American Association of Critical-Care Nurses

Paradis E, Leslie M, Puntillo K, Gropper M, Aboumatar HJ, Kitto S, Reeves S

Say no to old blood*.

Critical care medicine

Gilliss BM, Gropper MA

Applying ethnography to the study of context in healthcare quality and safety.

BMJ quality & safety

Leslie M, Paradis E, Gropper MA, Reeves S, Kitto S

ICU early mobilization: from recommendation to implementation at three medical centers.

Critical care medicine

Engel HJ, Needham DM, Morris PE, Gropper MA

Interprofessional care in intensive care settings and the factors that impact it: results from a scoping review of ethnographic studies.

Journal of critical care

Paradis E, Leslie M, Gropper MA, Aboumatar HJ, Kitto S, Reeves S

Exploring the nature of interprofessional collaboration and family member involvement in an intensive care context.

Journal of interprofessional care

Paradis E, Reeves S, Leslie M, Aboumatar H, Chesluk B, Clark P, Courtenay M, Franck L, Lamb G, Lyndon A, Mesman J, Puntillo K, Schmitt M, van Soeren M, Wachter B, Zwarenstein M, Gropper M, Kitto S

Risk factors and outcomes in transfusion-associated circulatory overload.

The American journal of medicine

Murphy EL, Kwaan N, Looney MR, Gajic O, Hubmayr RD, Gropper MA, Koenigsberg M, Wilson G, Matthay M, Bacchetti P, Toy P

Challenge of assessing symptoms in seriously ill intensive care unit patients: can proxy reporters help?

Critical care medicine

Puntillo KA, Neuhaus J, Arai S, Paul SM, Gropper MA, Cohen NH, Miaskowski C

Central venous catheters: follow the evidence, not the guidelines.

Critical care medicine

Lipshutz AK, Gropper MA

Organ donation after cardiac death in amyotrophic lateral sclerosis.

Annals of neurology

Toossi S, Lomen-Hoerth C, Josephson SA, Gropper MA, Roberts J, Patton K, Smith WS

Fresh and stored red blood cell transfusion equivalently induce subclinical pulmonary gas exchange deficit in normal humans.

Anesthesia and analgesia

Weiskopf RB, Feiner J, Toy P, Twiford J, Shimabukuro D, Lieberman J, Looney MR, Lowell CA, Gropper MA

Transfusion-related acute lung injury: incidence and risk factors.

Blood

Toy P, Gajic O, Bacchetti P, Looney MR, Gropper MA, Hubmayr R, Lowell CA, Norris PJ, Murphy EL, Weiskopf RB, Wilson G, Koenigsberg M, Lee D, Schuller R, Wu P, Grimes B, Gandhi MJ, Winters JL, Mair D, Hirschler N, Sanchez Rosen R, Matthay MA

Reducing noninfectious risks of blood transfusion.

Anesthesiology

Gilliss BM, Looney MR, Gropper MA

Prediction is very difficult, especially about the future-Niels Bohr.

Critical care medicine

Donovan AL, Gropper MA

Critical care issues in patients after liver transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Razonable RR, Findlay JY, O'Riordan A, Burroughs SG, Ghobrial RM, Agarwal B, Davenport A, Gropper M

Symptoms experienced by intensive care unit patients at high risk of dying.

Critical care medicine

Puntillo KA, Arai S, Cohen NH, Gropper MA, Neuhaus J, Paul SM, Miaskowski C

Special article: rescue therapies for acute hypoxemic respiratory failure.

Anesthesia and analgesia

Liu LL, Aldrich JM, Shimabukuro DW, Sullivan KR, Taylor JM, Thornton KC, Gropper MA

Can we predict pulmonary complications after thoracic surgery?

Anesthesia and analgesia

Aldrich JM, Gropper MA

Ventilator-associated pneumonia in a neurologic intensive care unit does not lead to increased mortality.

Neurocritical care

Josephson SA, Moheet AM, Gropper MA, Nichols AD, Smith WS

Looking forward, looking back: assessing variations in hospital resource use and outcomes for elderly patients with heart failure.

Circulation. Cardiovascular quality and outcomes

Ong MK, Mangione CM, Romano PS, Zhou Q, Auerbach AD, Chun A, Davidson B, Ganiats TG, Greenfield S, Gropper MA, Malik S, Rosenthal JT, Escarce JJ

Noisy mechanical ventilation: listen to the melody.

Anesthesiology

Shimabukuro DW, Gropper MA

Perioperative glycemic control: an evidence-based review.

Anesthesiology

Lipshutz AK, Gropper MA

Postoperative infectious complications of abdominal solid organ transplantation.

Journal of intensive care medicine

Hlava N, Niemann CU, Gropper MA, Melcher ML

Strategies for success: A PDSA analysis of three QI initiatives in critical care.

Joint Commission journal on quality and patient safety

Lipshutz AK, Fee C, Schell H, Campbell L, Taylor J, Sharpe BA, Nguyen J, Gropper MA

The curse of the drinking class.

Critical care medicine

Yost CS, Gropper MA

Tracheostomy protocol compliance: herding cats?

Critical care medicine

Liu L, Gropper MA

The epithelium in acute lung injury/acute respiratory distress syndrome.

Current opinion in critical care

Gropper MA, Wiener-Kronish J

Critical care challenges in orthopedic surgery patients.

Critical care medicine

Taylor JM, Gropper MA

Recombinant factor VIIa reduces transfusion requirements in liver transplant patients with high MELD scores.

Transfusion medicine (Oxford, England)

Niemann CU, Behrends M, Quan D, Eilers H, Gropper MA, Roberts JP, Hirose R

Establishing a comprehensive, evidence-based protocol for the care of patients with sepsis.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

Fee C, Gropper MA

Impact of a series of interventions in vancomycin prescribing on use and prevalence of vancomycin-resistant enterococci.

Joint Commission journal on quality and patient safety

Guglielmo BJ, Dudas V, Maewal I, Young R, Hilts A, Villmann M, Gibbs L, Gropper M, Jacobs R

Transfusion-related acute lung injury: a review.

Chest

Looney MR, Gropper MA, Matthay MA

Look before you leap: how do intensivists improve care for critically ill patients?

The American journal of medicine

Gropper MA, Matthay MA

Injury and repair in lung and airways.

Critical care medicine

Shimabukuro DW, Sawa T, Gropper MA

Predicting mortality in acute respiratory distress syndrome: circulatory system knows best.

Critical care medicine

Misset B, Gropper MA, Wiener-Kronish JP

The alveolar epithelium: suspect or innocent bystander?

Anesthesiology

Gropper MA, Wiener-Kronish J

Respiratory and Hemodynamic Management After Cardiac Surgery.

Current treatment options in cardiovascular medicine

Liu LL, Gropper MA

Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia.

The Journal of clinical investigation

Kurahashi K, Kajikawa O, Sawa T, Ohara M, Gropper MA, Frank DW, Martin TR, Wiener-Kronish JP

Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury.

Nature medicine

Sawa T, Yahr TL, Ohara M, Kurahashi K, Gropper MA, Wiener-Kronish JP, Frank DW

Evaluation of antimicrobial and lipopolysaccharide-neutralizing effects of a synthetic CAP18 fragment against Pseudomonas aeruginosa in a mouse model.

Antimicrobial agents and chemotherapy

Sawa T, Kurahashi K, Ohara M, Gropper MA, Doshi V, Larrick JW, Wiener-Kronish JP

In vitro cellular toxicity predicts Pseudomonas aeruginosa virulence in lung infections.

Infection and immunity

Sawa T, Ohara M, Kurahashi K, Twining SS, Frank DW, Doroques DB, Long T, Gropper MA, Wiener-Kronish JP

Halogenated anesthetics and the injured lung: clouds on the horizon?

Anesthesiology

Wiener-Kronish JP, Gropper MA

IL-10 improves lung injury and survival in Pseudomonas aeruginosa pneumonia.

Journal of immunology (Baltimore, Md. : 1950)

Sawa T, Corry DB, Gropper MA, Ohara M, Kurahashi K, Wiener-Kronish JP

Intraluminal water increases expression of plasmid DNA in rat lung.

Human gene therapy

Sawa T, Miyazaki H, Pittet JF, Widdicombe JH, Gropper MA, Hashimoto S, Conrad DJ, Folkesson HG, Debs R, Forsayeth JR, Fox B, Wiener-Kronish JP

Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues.

Journal of cell science

Frigeri A, Gropper MA, Umenishi F, Kawashima M, Brown D, Verkman AS

Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes.

Proceedings of the National Academy of Sciences of the United States of America

Frigeri A, Gropper MA, Turck CW, Verkman AS

Acute cardiogenic pulmonary edema.

Clinics in chest medicine

Gropper MA, Wiener-Kronish JP, Hashimoto S

Pulmonary arterial and venous constriction during hypoxia in 3- to 5-wk-old and adult ferrets.

Journal of applied physiology (Bethesda, Md. : 1985)

Raj JU, Hillyard R, Kaapa P, Gropper M, Anderson J

The adult respiratory distress syndrome: definition and prognosis, pathogenesis and treatment.

British journal of anaesthesia

Wiener-Kronish JP, Gropper MA, Matthay MA

[Estimation of the filtration variables in the rat lung].

Nihon Kyobu Shikkan Gakkai zasshi

Tanita T, Gropper MA, Staub NC, Koike K, Nakada T

Lung expansion and the perialveolar interstitial pressure gradient.

Journal of applied physiology (Bethesda, Md. : 1985)

Bhattacharya J, Gropper MA, Shepard JM

Relationship of pleural effusions to increased permeability pulmonary edema in anesthetized sheep.

The Journal of clinical investigation

Wiener-Kronish JP, Broaddus VC, Albertine KH, Gropper MA, Matthay MA, Staub NC

Alveolar liquid and protein clearance from normal dog lungs.

Journal of applied physiology (Bethesda, Md. : 1985)

Berthiaume Y, Broaddus VC, Gropper MA, Tanita T, Matthay MA

Filtration profile in isolated zone 1 and zone 3 dog lungs at constant high alveolar pressure.

Journal of applied physiology (Bethesda, Md. : 1985)

Gropper MA, Bhattacharya J, Staub NC

Lung microvascular pressure profile measured by micropuncture in anesthetized dogs.

Journal of applied physiology (Bethesda, Md. : 1985)

Shepard JM, Gropper MA, Nicolaysen G, Staub NC, Bhattacharya J

Direct measurement of blood pressure within the long hypophysial portal blood vessels.

Neuroendocrinology

Findell PR, Mulchahey JJ, Shepard JM, Gropper MA, Battacharya J, Weiner RI

Pleural liquid pressure in dogs measured using a rib capsule.

Journal of applied physiology (Bethesda, Md. : 1985)

Wiener-Kronish JP, Gropper MA, Lai-Fook SJ

Interstitial fluid pressure gradient measured by micropuncture in excised dog lung.

Journal of applied physiology: respiratory, environmental and exercise physiology

Bhattacharya J, Gropper MA, Staub NC

Micropuncture measurement of lung microvascular pressure profile during hypoxia in cats.

Circulation research

Nagasaka Y, Bhattacharya J, Nanjo S, Gropper MA, Staub NC

Effect of lung inflation on alveolar-airway barrier protein permeability in dog lung.

Journal of applied physiology: respiratory, environmental and exercise physiology

Conhaim RL, Gropper MA, Staub NC